Throughout years of research, Algenis has confirmed that sodium channels blocking molecules can be used in the treatment of diverse pathologies acting many times as analgesic and/or muscle relaxant.
These molecules work in the following way:
Sodium channels blockers inhibit the passage of sodium through the cell membrane. This blocking prevents or delays the speed and amplitude of the membrane depolarization, which causes a change in the conduction of the nerve impulse. This process leads to the release inhibition in the motor plate of the acetylcholine neurotransmitter. In some cases, physiologically it causes the muscle to be unable to contract, causing its partial or total paralysis.
Algenis works with the molecules of paralyzing shellfish poison (PSP), which are a wide group of natural alkaloids that act by blocking the voltage-gated sodium channels (VGSC). Specifically, it works with the Gonyautoxins that block site 1 of the VGSC. The PPS is mainly associated with marine dinoflagellates (unicellular algae) and cyanobacteria (organisms with characteristics of bacteria and algae), which flourish in many parts of the world.